The Giallorossi has been struggling with injuries to several key players in recent weeks.
“Totti will definitely play, and I can say this because I have spoken to him and seen him in training,” Spalletti declared in an interview with the Roma Channel.
“He got through training very well, and the things he did on the track were all very positive, so the signs are looking good.
“He always wants to be out there playing, and especially in a match as significant as this, so for that reason, I know he will play this weekend.”