Stoke striker Mamady Sidibe will be out of action for up to a year while record signing Kenwyne Jones is struggling with a minor injury.
“Mamady will be out for a year and that’s a massive disappointment because the effort and commitment he puts in for us every week is just first class,” said Pulis.
“We’ve already lost Kenwyne Jones for the trip to Chelsea and though it’s not going to be the six or seven months we first feared, it’s still a ligament injury that could be another two or three weeks.
“We’re looking to bring in another three or four players but this has been our toughest start since we came back up.”