Sevilla could face a rematch with the team they beat in the final of the competition last year, Atletico Madrid, though Los Colchonerones will need to overturn a 3-1 deficit from their first leg away to Real Madrid.
The other semi final is likely to be between Barcelona, who beat Real Betis 5-0 in their first leg, and Almeria or Deportivo, with Almeria holding a 1-0 advantage in that tie.