Santos beat Colo-Colo 3-2 last week but had three players sent off including star man Neymar, who received a second yellow card for celebrating a goal by brandishing a plastic mask of his own face.
Interim boss Marcelo Martelotte said: “Muricy has no choice but to work on those three problems for the next game. But I have no doubt we have been strengthened by this win over Colo Colo to face Cerro Porteno.”