Sevilla failed with an attempt to sign the 22-year-old Mexican forward in the summer.
Sevilla sporting director Ramon Rodriguez told Spanish TV: “It’s a difficult subject, but not impossible.
“The agents have offered us 50 per cent of the rights but the price imposed by Tottenham must be ignored.
“That is the doubt.
“We believe Giovani wants to leave Tottenham and that could be decisive.
“He was our first choice in the summer but Tottenham wanted too much money for a deal.”