Wayne Rooney scored the first goal while Berbatov the next two in Denmark.
Rafael, Wayne Rooney and Paul Scholes did all leave the pitch with injuries during the match. Scholes suffered a knee ligament damage, but it is unsure the nature of the other injuries.
Robin van Persie and Emmanuel Adebayor scored two each as they crushed FC Porto at home in London.
Juventus was two goals down away against BATE, but with two goals by Iaquinta they managed to get a draw.
Ruud van Nistelrooy scored the winner as Real Madrid managed to get all three points with them from Russia.
Zenit 1-2 Real Madrid
Aalborg 0-3 Manchester United
Arsenal 4-0 FC Porto
BATE 2-2 Juventus
Bayern Munich 1-1 Lyon
Fenerbahce 0-0 Dynamo Kiev
Fiorentina 0-0 Steaua Bucharest
Villarreal 1-0 Celtic