Bosingwa has recovered from a knee injury that has kept him out of action for around a year.
Didier Drogba is also set to return to action.
“I can say that Bosingwa will start – this is very good news after a long period,” said Chelsea boss Carlo Ancelotti.
“Everyone is excited to see him back and he’s a very important player. We need a full-back with power and resistance. He has all these skills. Drogba will come back. He is fit and able to play.”