Giggs, who will be 36 in November, has impressed for United this season and is just one goal away from becoming only the 17th player to score 100 Premier League goals.
The former Wales international has won 11 championship titles since making his debut in March 1991.
“We have had a lot of top-class players in this league – and some have probably made more of an impact than Ryan – but nobody can boast the same sort of longevity and consistency,” said the United boss.
“He was there when the league started and he is still there now. I think you would have to say Ryan is the best.”
“We have played him out wide in a few games recently because he is fresh at the moment,” Ferguson told Inside United.
“It’s the beginning of the season so he has got plenty of running in him and he can do a lot of damage in the wide position.
“But I think you will find as the season progresses he will move back into the middle of the park where he can dictate the games.”