Tuttosport claim Real Madrid will consider selling the midfielder for around 40million euros.
Isco is good friends with Juventus forward Alvaro Morata and the Italian side will use their friendship to convince the midfielder to move to Turin.
Reports claim Real Madrid would like to get an option on highly-rated midfielder Paul Pogba as part of the deal for Isco.
Arsenal, Manchester City and Chelsea are also reportedly interested in the midfielder.
