The summer signing from Tottenham did not turn up at Anfield after manager Rafael Benitez replaced him with French youngster David Ngog on the bench.
Benitez said: “We have a good squad and Keane was not selected.
“I have not seen him so I don’t know how he has reacted. But every player wants to be involved so I would expect he is not happy.
“Ngog scored twice for the reserves in their last match, so he was a good option. And we have Ryan Babel and Lucas who can play forward, so we were well covered.”