Liverpool won three matches and did not concede a single goal against PSV, when they reached the 2007 Champions League final.
Kuyt said: “They are very different from the last time we played against them.
“Heurelho Gomes, the goalkeeper, is now at Spurs, Phillip Cocu has retired and a lot of other players have also gone to other clubs.
“They are a totally different side but they are still the best in Holland.
“They have won the league four times in a row, so they’re a very good team and we have to be ready.”