United plan to bring in Gladstony, Aguilar, Lucas Evangelista, Agnaldo and Rafael Leao, who watched the win over Bolton last weekend at Old Trafford.
United will use Dutch giants FC Twente has a holding club for the Brazilian youngsters.
United have an agreement with Sao Paulo academy Desportivo and the company’s president of international business Jochen Losh has confirmed their partnership with the Premier League giants.
“Twente are a partner, helping United to resolve the problem of their EU passports,” Losch told the Daily Mail.
“For two reasons it’s good that a player goes first to Holland. First, after two or three years he’s considered to be European. And, of course, it’s easier to play in the Dutch league than the Premier League.”
He added: “Manchester United look for young players in Brazil, Argentina, Uruguay and Paraguay.
“If they find a good one they come to us. We’ll get a player, register him with Desportivo Brasil, and we have a contract with United that they have an option to buy this player at 18 for a fixed amount.
“If the guy turns out to be an Alexandre Pato, United can still have him for a huge discount because of course we’ll honour the contract. If they don’t like the player, we keep him.”