Ferdinand was forced off in United’s win over Fulham on Monday with a back problem.
“It’ll be the same squad as Monday night with no changes,” said Ferguson.
“We expect Nani to train tomorrow but the game will come too soon for him.
“Rio is okay, he just felt a bit stiff. We know the situation with that. We addressed it right away and put Chris Smalling on. He’s fine.”
“The game at Blackburn is always a difficult type of game,” added Ferguson. “It has a local derby feeling about it and is always a bit feisty.
“Last season, we came back from a goal down to win the league but we expect a difficult game. That’s the way all the matches will be but hopefully we can navigate them.”
