United boss Sir Alex Ferguson is reportedly saving the England international for the Premier League clash with Manchester City on Sunday.
Ferdinand was rested for United’s trip to Benfica last month as well and has not been a regular in the side this season.
United skipper Nemanja Vidic has travelled with the United squad for the clash in Romania and could return to action following a recent calf problem.
Tom Cleverley (foot) and Rafael (shoulder) will also miss the clash against Otelul Galati.
