Dimitar Berbatov, Ryan Giggs and Nemanja Vidic are all expected to be fit for the game against the Blues.
Wayne Rooney and Patrice Evra came on as substitutes in the thrilling draw with CSKA Moscow and should start against Chelsea.
Rio Ferdinand remains doubtful for the Red Devils.
“I think we’re ready for Sunday,” Ferguson told Sky Sports. “Our form going into the game is good.
“We have some players to come back.
“Patrice had 30 minutes (against CSKA) and Wayne had 30 minutes. Berbatov should be fit for Sunday, Giggs should be fit and Vidic will probably be fit.
“We have players coming back, we are fresh and looking good.”