Chris Smalling and Ashley Young are also included in the squad for the clash with the Dutch giants.
Ryan Giggs, Dimitar Berbatov and Patrice Evra have not been included in the squad.
Manchester United squad: De Gea, Amos; Fabio, Rafael, Evans, Jones, Smalling, Fryers, Ferdinand; Valencia, Nani, Carrick, Young, Park, Scholes, Cleverley, Pogba; Rooney, Hernandez, Welbeck.