Best sustained a knee injury in Sunday’s 2-1 win over Aston Villa.
“Leon has got a medial ligament injury, which is usually a six-week lay-off,” said Pardew.
Ryan Taylor was also taken off, but the reason was a ‘big swelling on the leg’.
“The good news for Ryan Taylor is that there is no break or fracture, so we think he’s going to be OK,” added Pardew.
