The Toffees have the chance to reach the final for the first time since 1995.
“This game will definitely be one of the biggest games I have played in,” said Pienaar.
“I have been involved in a lot of important games at my two previous clubs but I believe this one will also go down in the history books for Everton and I’m looking forward to it.
“When I was at Borussia Dortmund, we used to play every weekend in front of 83,000, so this occasion will not concern me.
“At Ajax, we played AC Milan in the Champions League at the San Siro, which was also pretty impressive.
“But, for me, this is like a normal game, it is just that it’s a semi-final.”
He added: “Manchester United are not only the top team in England but in Europe also.
“But sometimes a side has a dip in form and in the last few games they have not done so well, but they can turn it around in a second. We just have to go out and play our own game and not worry about them.”
