Both players are uncapped and were surprise inclusions by Spain head coach Vicente del Bosque.
The clash will take place in Sevilla next week.
Squad in full:
Goalkeepers: Iker Casillas (Real Madrid), Jose Reina (Liverpool).
Defenders: Raul Albiol (Valencia), Alvaro Arbeloa (Liverpool), Joan Capdevila (Villarreal), Juanito (Real Betis),Carlos Marchena (Valencia), Carles Puyol (Barcelona), Sergio Ramos (Real Madrid), Gerard Pique (Barcelona).
Midfielders: David Silva (Valencia), Xabi Alonso (Liverpool), Santi Cazorla (Villarreal), Sergio Busquets (Barcelona), Xavi (Barcelona), Andres Iniesta (Barcelona), Albert Riera (Liverpool), Marcos Senna (Villarreal).
Forwards: David Villa (Valencia), Daniel Guiza (Fenerbahce), Fernando Torres (Liverpool), Fernando Llorente (Athletic Bilbao).
