Falcao has scored three times for Porto in the Champions League this season.
Falcao said: “Arsenal are the favourites and that will suit us because it puts extra pressure on our opponents.
“Normally both teams score goals but now we’re into the knock-out stages it will be tight, necessary to play with your head and even though Arsenal are a big club I’m happy we avoided the big teams of Spain.
“This is a tie we can win and also at the same time prove that Portugal has good teams which are ready for big challenges.”