The Russians suffered a 4-1 defeat to Chelsea at Stamford Bridge on Wednesday.
Spartak face Marseille on Matchday Five of the Champions League, a game that could decide if the Russian’s will reach the knock-out phase.
“Nothing has changed in terms of our chances of getting out of the group,” said Karpin.
“If we win our last two games, we will qualify. When you’re losing 4-1, there’s not much joy in having scored at Stamford Bridge. It would only have been significant if the score had been 0-0 at the time.
“The main positive was us gaining experience. We have a young team and they’ve played one of the best teams in Europe, maybe one of the best in the world.
“These players can look up to the best players in the world and see how technical they are, how well they can play, and benchmark themselves against them.”
