Sevilla boss Marcellino Garcia Toral is keen to bring in the 22-year-old winger. Dos Santos spent time on loan at Racing Santander last season, while Garcia Toral was in charge at the club.
“I want to play in Sevilla. It is my main preference and this possibility exists but the subject is still not closed,” he told Spanish website El Desmarque.
“I am still in London but Tottenham desire my sale. My agent is working hard and I hope for a solution next week.
“I prefer La Liga to other countries. I was happy with Marcelino in Santander and it will be sensational to repeat the experience with Sevilla – one of the best European clubs.
He added: “To play next to Frederic Kanoute would be a pleasure.”