Vidic has been struggling with a calf injury during pre-season and is expected to be out for up to two more weeks.
Gary Neville, Wes Brown and Edwin van der Sar is also struggling with injury worries.
“Everyone is fit apart from Wes, Vidic and Neville,” said Ferguson.
“Gary has done a bit of training, and he is coming along fine. And I expect Wes to be fit for the Birmingham match.
“Vidic is another week or two away and Edwin’s injury is a bad one. He’s out for 8-10 weeks, of course. So my first selection dilemma for Sunday is in goal.”
